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Publications

Affichage des publications 381 à 390 sur 710 au total

Sciences cognitives

Dopaminergic neuromodulation of prefrontal cortex activity requires the NMDA receptor coagonist d-serine

Prefrontal control of cognitive functions critically depends upon glutamatergic transmission and N-methyl D-aspartate (NMDA) receptors, the activity of which is regulated by dopamine. Yet whether the NMDA receptor coagonist d -serine is implicated…

Glenn Dallérac, Xia Li, Pierre Lecouflet, Nadège Morisot, Silvia Sacchi, Rachel Asselot, Thu Ha Pham, Brigitte Potier, David Watson, Staffan Schmidt, Grégoire Levasseur, Pascal Fossat, Andrey Besedin, Jean-Michel Rivet, Joseph Coyle, Ginetta Collo, Loredano Pollegioni, Jan Kehr, Micaela Galante, Kevin Fone, Alain Gardier, Thomas Freret, Angelo Contarino, Mark Millan, Jean-Pierre Mothet

Proceedings of the National Academy of Sciences of the United States of America -

Neurobiologie

Astrocytic VMAT2 in the developing prefrontal cortex is required for normal grooming behavior in mice

Abstract Astrocytes control synaptic activity by modulating peri-synaptic concentrations of ion and neurotransmitters including dopamine and, as such, can be critically involved in the modulation of some aspect of mammalian behavior. Here we report…

Francesco Petrelli, Tamara Zehnder, Luca Pucci, Corrado Cali, Bianca Maria Bondiolotti, Alicia Molinero Perez, Glenn Dallerac, Nicole Déglon, Bruno Giros, Fulvio Magara, Lorenzo Magrassi, Jean-Pierre Mothet, Linda Simmler, Paola Bezzi

Neurosciences

P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy

Alzheimer's disease is the most common form of dementia characterized by intracellular aggregates of hyperphosphorylated Tau protein and extracellular accumulation of amyloid β (Aβ) peptides. We previously demonstrated that the purinergic receptor…

Kevin Carvalho, Elodie Martin, Aurélia Ces, Nadège Sarrazin, Pauline Lagouge-Roussey, Caroline Nous, Leyna Boucherit, Ihsen Youssef, Annick Prigent, Emilie Faivre, Sabiha Eddarkaoui, Thibaut Gauvrit, Didier Vieau, Susana Boluda, Vincent Huin, Bertrand Fontaine, Luc Buée, Benoît Delatour, Patrick Dutar, Florian Sennlaub, Xavier Guillonneau, David Blum, Cécile Delarasse

Progress in Neurobiology -

Physique

Spin-Mechanics with Nitrogen-Vacancy Centers and Trapped Particles

Controlling the motion of macroscopic oscillators in the quantum regime has been the subject of intense research in recent decades. In this direction, opto-mechanical systems, where the motion of micro-objects is strongly coupled with laser light…

Maxime Perdriat, Clément Pellet-Mary, Paul Huillery, Loïc Rondin, Gabriel Hétet

Micromachines -

Génomique, Transcriptomique et Protéomique

Antimicrobial d-amino acid oxidase-derived peptides specify gut microbiota

Abstract The flavoenzyme d -amino acid oxidase (DAAO) is deputed to the degradation of d -enantiomers of amino acids. DAAO plays various relevant physiological roles in different organisms and tissues. Thus, it has been recently suggested that the…

Giulia Murtas, Silvia Sacchi, Gabriella Tedeschi, Elisa Maffioli, Eugenio Notomista, Valeria Cafaro, Monica Abbondi, Jean-Pierre Mothet, Loredano Pollegioni

Cellular and Molecular Life Sciences -