Publié

Sciences du Vivant

In vitro space of Disse model for exploration of drug induced hepatotoxicity

Publié le - Lab on a Chip

Auteurs : Ana Mesic, Antonietta Messina, Zoe Tiprez, Benoit Charlot, Safa Mohamed Ismail, Nicolas Huang, Sakina Bensalem, Jean-Charles Duclos-Vallee, Bruno Le Pioufle

Voir la publication sur HAL DOI

A human-cell-derived liver-on-a-chip model integrating tunable alginate hydrogel and LSEC–HepaRG co-culture. Recapitulates sinusoidal architecture, with an emphasis on intercellular communication in the space of Disse.