Raspberry-like small multicore gold nanostructures for efficient photothermal conversion in the first and second near-infrared windows

Gold nanoraspberries were synthesized by a seed-mediated synthesis with polyethylene glycol-functionalized bisphosphonates. The original structure shifted the optical absorption to infrared, revealing very efficient photothermal properties within the 2nd biological transparency window and leading to cancer cell necrosis at moderate intracellular doses and low (safe) laser power.